Bipolar electrode probe for ablation monitoring

ABSTRACT

An electromagnetic surgical ablation system having a generator adapted to selectively provide surgical ablative energy to an ablation probe, and methods of operating same, are disclosed. The system includes a controller operatively coupled to the generator, and at least one tissue sensor probe operatively coupled to the controller. The at least one tissue sensor provides a tissue impedance measurement to the controller. A sensor probe may be designated a threshold probe adapted to sense when tissue is sufficiently ablated, or, a critical structure probe adapted to protect an adjacent anatomical structure from undesired ablation. During an electromagnetic tissue ablation procedure, the controller monitors tissue impedance to determine tissue status, to activate an indicator associated therewith, and, additionally or alternatively, to activate and deactivate the generator accordingly.

CROSS-REFERENCE TO RELATED APPLICATIONS

The present application is a divisional application, which claims priority to, and the benefit of, U.S. patent application Ser. No. 12/708,974, filed on Feb. 19, 2010, the disclosure of which is herein incorporated by reference in its entirety.

BACKGROUND

1. Technical Field

The present disclosure relates to systems and methods for providing energy to biological tissue and, more particularly, to apparatus and methods for sensing one or more properties of tissue at one or more locations during a microwave ablation procedure.

2. Background of Related Art

Energy-based tissue treatment is well known in the art. Various types of energy (e.g., electrical, ultrasonic, microwave, cryogenic, thermal, laser, etc.) are applied to tissue to achieve a desired result. Electrosurgery involves application of high radio frequency electrical current to a surgical site to cut, ablate, coagulate or seal tissue. In monopolar electrosurgery, a source or active electrode delivers radio frequency energy from the electrosurgical generator to the tissue and a return electrode mines the current back to the generator. In monopolar electrosurgery, the source electrode is typically part of the surgical instrument held by the surgeon and applied to the tissue to be treated. A patient return electrode is placed remotely from the active electrode to carry the current back to the generator. In tissue ablation electrosurgery, the radio frequency energy may be delivered to targeted tissue by an antenna or probe.

There are several types of microwave antenna assemblies in use, e.g., monopole, dipole and helical, which may be used in tissue ablation applications. In monopole and dipole antenna assemblies, microwave energy generally radiates perpendicularly away from the axis of the conductor. Monopole antenna assemblies typically include a single, elongated conductor. A typical dipole antenna assembly includes two elongated conductors, which are linearly aligned and positioned end-to-end relative to one another with an electrical insulator placed therebetween. Helical antenna assemblies include a helically-shaped conductor connected to a ground plane. Helical antenna assemblies can operate in a number of modes including normal mode (broadside), in which the field radiated by the helix is maximum in a perpendicular plane to the helix axis, and axial mode (end fire), in which maximum radiation is along the helix axis. The tuning of a helical antenna assembly may be determined, at least in part, by the physical characteristics of the helical antenna element, e.g., the helix diameter, the pitch or distance between coils of the helix, and the position of the helix in relation to the probe assembly to which it is mounted.

The typical microwave antenna has a long, thin inner conductor that extends along the longitudinal axis of the probe and is surrounded by a dielectric material and is further surrounded by an outer conductor around the dielectric material such that the outer conductor also extends along the axis of the probe. In another variation of the probe that provides for effective outward radiation of energy or heating, a portion or portions of the outer conductor can be selectively removed. This type of construction is typically referred to as a “leaky waveguide” or “leaky coaxial” antenna. Another variation on the microwave probe involves having the tip formed in a uniform spiral pattern, such as a helix, to provide the necessary configuration for effective radiation. This variation can be used to direct energy in a particular direction, e.g., perpendicular to the axis, in a forward direction (i.e., towards the distal end of the antenna), or combinations thereof.

Invasive procedures and devices have been developed in which a microwave antenna probe may be either inserted directly into a point of treatment via a normal body orifice or percutaneously inserted. Such invasive procedures and devices potentially provide better temperature control of the tissue being treated. Because of the small difference between the temperature required for denaturing malignant cells and the temperature injurious to healthy cells, a known heating pattern and predictable temperature control is important so that heating is confined to the tissue to be treated. For instance, hyperthermia treatment at the threshold temperature of about 41.5° C. generally has little effect on most malignant growth of cells. However, at slightly elevated temperatures above the approximate range of 43° C. to 45° C., thermal damage to most types of normal cells is routinely observed. Accordingly, great care must be taken not to exceed these temperatures in healthy tissue.

In the case of tissue ablation, a high radio frequency electrical current in the range of about 500 MHz to about 10 GHz is applied to a targeted tissue site to create an ablation volume, which may have a particular size and shape. Ablation volume is correlated to antenna design, antenna tuning, antenna impedance and tissue impedance. Tissue impedance may change during an ablation procedure due to a number of factors, e.g., tissue denaturization or desiccation occurring from the absorption of microwave energy by tissue. Changes in tissue impedance may cause an impedance mismatch between the probe and tissue, which may affect delivery of microwave ablation energy to targeted tissue. The temperature and/or impedance of targeted tissue, and of non-targeted tissue and adjacent anatomical structures, may change at varying rates which may be greater, or less than, expected rates. A surgeon may need to perform an ablation procedure in an incremental fashion in order to avoid exposing targeted tissue and/or adjacent tissue to excessive temperatures and/or denaturation. In certain circumstances, a surgeon may need to rely on experience and/or published ablation probe parameters to determine an appropriate ablation protocol (e.g., ablation time, ablation power level, and the like) for a particular patient.

SUMMARY

The present disclosure is directed to an electromagnetic surgical ablation system that includes one or more tissue sensor probes adapted to sense a tissue property, e.g., tissue impedance, at or near an ablation surgical site. Also disclosed is a controller module which may include a sensor interface having one or more sensor inputs adapted to receive a sensor signal from the one or more tissue sensor probes. Additionally or alternatively, one or more sensor interfaces may be provided by the controller module. The disclosed sensor interface may include an impedance measurement circuit that is adapted to perform a conversion of a raw signal, which may be received from the one or more tissue sensor probes, into an impedance measurement suitable for processing by a processor included within the controller.

The disclosed surgical ablation system may include a source of microwave ablation energy, such as a generator, that is responsive to a control signal generated by the control module. The one or more tissue sensor probes, the controller, and the generator function cooperatively to enable a surgeon to monitor one or more tissue properties at, or adjacent to, an ablation surgical site. Additionally or alternatively, the described arrangement may enable the automatic control, activation, and/or deactivation of ablative energy applied to tissue to enable precise control over the ablation size and/or volume created during an ablation procedure.

In addition, the present disclosure provides an electromagnetic surgical ablation system having a generator adapted to selectively provide surgical ablative energy to an ablation probe. The ablation probe is operably coupled to the generator and adapted to receive ablative energy therefrom, and to deliver said ablative energy to targeted tissue, e.g., a tumor, polyp, or necrotic lesion. The disclosed system includes a controller operatively coupled to the generator, the controller including at least one processor, a memory operatively coupled to the processor, a sensor interface circuit operatively coupled to the processor and adapted to receive one or more impedance sensor signals from one or more tissue sensor probes. Additionally or alternatively, a tissue sensor probe may include additional sensor, such as without limitation, a temperature sensor. In such an embodiment, the sensor interface circuit may include a temperature sensor circuit operatively coupled to the processor and adapted to receive a temperature sensor signal from a tissue sensor probe.

In one aspect, a system in accordance with the present disclosure may enable a surgeon to place one or more tissue sensor probes around a targeted ablation region, and/or between a targeted ablation region and an adjacent anatomical structure. During an ablation procedure, the controller may monitor the one or more sensors to track the progress of the ablation region as tissue is “cooked”, based at least in part upon an impedance change detected at the one or more probe locations. In an embodiment, a feedback signal may be provided to the surgeon, e.g., a visual, audible, and/or tactile indication, such that a surgeon may follow the ablation region formation in real-time or in near-real-time. Each probe may be positioned such that targeted tissue may be monitored at various locations around, and/or distances from, an ablation probe being utilized to deliver ablative energy to tissue.

A tissue sensor probe may be identified (e.g., assigned or tagged) and/or adapted as a “threshold” probe or a “critical structure” tag. It is envisioned that a threshold tag may be configured to sense when the tissue associated therewith has reached an ablation threshold, e.g., the point at which the desired degree of desiccation has occurred. As tissue associated with a given probe has reached the desired ablation state, an indicator associated with the sensor may be activated. When a plurality of threshold probes are utilized, a surgeon may recognize when an ablation procedure is completed by noting when all, or a sufficient number of, indicators associated with the various probes have been activated. In an embodiment, the controller may automatically deactivate a generator when all, or a sufficient number of, threshold probes have reached a predetermined threshold.

A probe identified as a “critical structure” probe may be configured to activate an indicator, which may be an alarm indicator, when tissue associated therewith is about to, but has not yet, received ablation energy in excess of a predetermined safety threshold. Additionally or alternatively, the disclosed system may be configured to automatically deactivate an ablation generator when a predetermined number (e.g., one or more) of indicators associated with a critical structure probe have been activated. While it is contemplated that a critical structure probe may be positioned between an operative field and an adjacent critical anatomical structure, it should be understood that the present disclosure is in no way limited to such use and that the described probes and features may be advantageously utilized in any combination for any purpose.

Also disclosed is a method of operating an electromagnetic surgical ablation system. The disclosed method includes the steps of activating an electrosurgical generator to deliver ablative energy to tissue and sensing a tissue impedance parameter from at least one tissue sensing probe, which may be inserted into tissue. A determination is made as to whether a sensed tissue impedance parameter exceeds a predetermined tissue impedance parameter threshold. In response to a determination that a sensed tissue impedance parameter exceeds a predetermined tissue impedance parameter threshold, an action is performed, e.g., the electrosurgical generator is deactivated and/or an indication is presented.

The present disclosure also provides a computer-readable medium storing a set of programmable instructions configured for being executed by at least one processor for performing a method of performing microwave tissue ablation in response to monitored tissue temperature and/or monitored tissue dielectric properties in accordance with the present disclosure.

BRIEF DESCRIPTION OF THE DRAWINGS

The above and other aspects, features, and advantages of the present disclosure will become more apparent in light of the following detailed description when taken in conjunction with the accompanying drawings in which:

FIG. 1 shows a diagram of a microwave ablation system having an electromagnetic surgical ablation probe and at least one tissue sensor probe in accordance with the present disclosure;

FIG. 2 shows a block diagram of a microwave ablation system having an electromagnetic surgical ablation probe and at least one tissue sensor probe in accordance with the present disclosure;

FIG. 3 is a perspective view of a tissue sensor probe in accordance with the present disclosure;

FIG. 4 is a side, cutaway view of a tissue sensor probe in accordance with the present disclosure;

FIG. 5 is a flowchart showing a method of operation of a microwave ablation system having one or more tissue sensor probes in accordance with the present disclosure; and

FIG. 6 illustrates a relationship between time, an impedance sensed by a first tissue sensor probe, and an impedance sensed by a second tissue sensor probe in accordance with the present disclosure.

DETAILED DESCRIPTION

Particular embodiments of the present disclosure are described hereinbelow with reference to the accompanying drawings; however, it is to be understood that the disclosed embodiments are merely exemplary of the disclosure, which may be embodied in various forms. Well-known functions or constructions are not described in detail to avoid obscuring the present disclosure in unnecessary detail. Therefore, specific structural and functional details disclosed herein are not to be interpreted as limiting, but merely as a basis for the claims and as a representative basis for teaching one skilled in the art to variously employ the present disclosure in virtually any appropriately detailed structure.

In the drawings and in the descriptions that follow, the term “proximal,” as is traditional, shall refer to the end of the instrument that is closer to the user, while the term “distal” shall refer to the end that is farther from the user.

FIG. 1 shows an embodiment of a microwave ablation system 10 in accordance with the present disclosure. The microwave ablation system 10 includes an electromagnetic surgical ablation probe 100 having a tapered distal tip 120 and a feed point 122. The ablation probe 100 is operably connected by a cable 15 to connector 16, which further operably connects probe 100 to a generator assembly 20. Generator assembly 20 may be a source of ablative energy, e.g., microwave or RF energy in the range of about 915 MHz to about 10 GHz. The disclosed system 10 includes one or more tissue sensor probes 200 that are adapted to sense one or more operative parameters, e.g., a tissue impedance. The tissue sensor probe 200 is operably connected by a cable 14 to a connector 18, which further operably connects tissue sensor probe 200 to a controller assembly 30. An actuator 40 is operably coupled to the controller to enable a user, e.g., a surgeon, to selectively activate and de-activate the delivery of ablative energy to patient tissue. Controller 30 is operably coupled to generator 20 to enable communication therebetween, such as without limitation, a control signal and/or a status signal.

In more detail, FIG. 2 illustrates a functional block diagram of an ablation system 10 in accordance with the present disclosure. The system 10 includes a controller 30 that includes one or more processors 31 operatively coupled to memory 32, storage device 33, sensor interface 34, and user interface 35. Processor 31 is configured to execute a set of programmed instructions for performing a method of microwave ablation as disclosed herein. Memory 32 and/or storage device 33 may include any suitable memory device, including without limitation, semiconductor memory (e.g., random-access memory, read-only memory, flash memory), hard disk, optical storage (e.g., CD-ROM, DVD-RAM, etc.), USB memory stick, and the like.

Controller 30 includes an actuator interface 36 that is adapted to facilitate operative coupling with actuator 40 and/or a generator interface 37 that is adapted to facilitate operative coupling with generator 20. Actuator 40 may be any suitable actuator, such as without limitation, a footswitch, a handswitch (which may be mounted on a probe 100 and/or a tissue sensor probe 200), an orally-activated switch (e.g., a bite-activated switch and/or a breath-actuated switch), and the like. The processor 31, memory 32, storage device 33, sensor interface 34, actuator interface 36 and/or generator interface 37 may be separate components or may be integrated, such as in one or more integrated circuits. The various components in the controller 30 are coupled by one or more communication buses or signal lines 38. Memory 30 and/or storage device 33 may include a set of executable instructions for performing a method of microwave ablation as described herein. One or more elements of ablation system 10 may be coupled using a hard-wired connection (e.g., copper wire and/or fiber optic media) and/or a wireless link. During use, the one or more tissue sensor probe 200 may be positioned in tissue T in proximity to probe 100 to obtain one or more tissue parameter(s), e.g., tissue impedance.

User interface 35 may include any suitable form of visual, audible, or tactile user interface elements, including without limitation, a graphic display panel (e.g., LCD, LED, OLED plasma, gas-discharge display, and the like), touchscreen, keypad, pushbutton, switch, lamp, annunciator, speaker, haptic feedback device, and so forth.

As shown in FIG. 2, and by way of example only, an ablation probe 100 is inserted into tissue T for use. A tissue sensor probe 200 is inserted into tissue T in a position generally adjacent to probe 200. Another tissue sensor probe 200′ is inserted into tissue T at a position further from probe 100. Yet a third tissue sensor probe 200″ is inserted into tissue T at a position generally between probe 100 and a critical anatomical structure CS. During use, ablative energy from probe 100 is delivered into tissue T to effectuate ablation of at least a part of tissue T. Denaturation of tissue T proceeds generally outwardly from feed point 122. As the volume of denatured (ablated) tissue expands, an impedance boundary expands in a corresponding manner.

It has been observed that during an initial phase of an ablation procedure, tissue impedance will remain relatively constant. As tissue approaches denaturation (e.g., as tissue becomes “cooked”), impedance tends to rise rapidly. By sensing the impedance at one or more points surrounding the ablation probe 100, the formation of the ablated volume of tissue may be accurately monitored. In turn, the delivery of ablative energy may be controlled in response to the one or more impedance measurements obtained from the surrounding tissue. Thus, a surgeon may define a desired ablation region by deliberately positioning one or more tissue sensor probes 200 at or near the outer boundaries of the desired region. As each probe 200 senses a rise in impedance (which may signify tissue denaturation has occurred), a corresponding indication may be presented to a user (e.g., a surgeon) that ablation of the tissue corresponding to the probe has completed. An indication may be presented via user interface 35. The defined ablation volume is deemed fully ablated once each designated tissue probe 200 has sensed an impedance rise corresponding to denaturation. An “ablation complete” indication may then be presented to the user, or, additionally or alternatively, the generator 20 may be automatically deactivated. In this manner, the ablation region may be precisely controlled with greatly reduced risk of over-ablation and/or excessive charring of tissue or injuring critical structures.

The tissue probe(s) 200 may be designated as a threshold probe or a critical structure probe. One or more threshold probes may be used to define an ablation volume by deliberate placement in tissue by a surgeon, as described hereinabove. The one or more threshold probe(s) may be grouped to define a threshold group, whereby an ablation complete status is established when each threshold probe in a group has sensed an impedance rise corresponding to tissue denaturation. In contrast, a critical structure probe may be used to recognize a pre-denaturation state of tissue, such as without limitation, an initial slight or gradual rise in impedance which may precede a more pronounced or rapid rise in impedance associated with tissue denaturation. In an embodiment, if any one critical structure probe senses pre-denaturation, an indicator may be presented to the user and/or generator 200 deactivated. In this manner, undesired ablation of one or more critical anatomical structures at or near the ablation site may be prevented.

A graph illustrating a relationship between sensor position, ablation time, and tissue impedance (shown generally as 400) is presented in FIG. 6, wherein a first impedance curve 405 corresponding to a first tissue sensor probe 200, and a second impedance curve 410 corresponding to a second tissue sensor probe 200′, are shown. Initially, as ablation energy is first delivered to tissue, both tissue sensor probes 200 and 200′ indicate a relatively constant impedance value 401. As ablation time t progresses, tissue surrounding first tissue sensor probe 200 begins to denature, as illustrated by a rise in impedance 406. As ablation continues, the volume of denatured tissue expands, and eventually, reaches second tissue sensor probe 200′, as illustrated by a second rise in impedance 411. Denaturation may be indicated by, e.g., an absolute rise in impedance, a change in impedance from an initial impedance value, and/or rate of change of impedance exceeding a predetermined rate.

Designation of a tissue probe 200 as a threshold probe or a critical structure probe may be accomplished manually by, e.g., a user entering the appropriate designation via user interface 35. Additionally or alternatively, a tissue probe 200 may include an identifier (not explicitly shown) that identifies to controller 30 the probe as a threshold probe, a critical structure probe, or a universal probe which may function as either a threshold probe or a critical structure probe. The identifier may include, without limitation, an RFID tag, a semiconductor memory device (e.g., ROM, EEPROM, NAND or NOR flash memory), an encoded electrical component (encoded resistor value), a mechanical identifier (e.g., physically encoded connector member), an optical identifier (e.g., a barcode) and the like. In an embodiment, a user entry may override an identifier-defined designation of a probe 200.

A tissue sensor probe 200 in accordance with an embodiment of the present disclosure is now described with reference to FIGS. 3 and 4. The disclosed tissue sensor probe 200 includes an elongated shaft 210 having a proximal end 213 and a distal end 211. A tapered tip 220 may be disposed at a distal end 211 of the probe 200 to facilitate the insertion of probe 200 into tissue. As shown, tapered tip 220 has a generally conical shape; however, any suitable tip shape may be utilized. A pair of electrodes 222, 224 are disposed on an exterior portion of the shaft 210. As shown, electrodes 222, 224 are substantially annular in shape and disposed coaxially about the shaft 210; however, other electrode arrangements are contemplated within the scope of the present invention, including without limitation, longitudinal electrodes, helical electrodes, dot-shapes electrodes, and so forth. Electrodes 222, 224 may be formed from any suitable biocompatible and electrically conductive material, such as without limitation, stainless steel. In an embodiment, electrodes 222, 224 are disposed generally toward a distal end 211 of the shaft 210; however, it is to be understood that either or both electrodes 222, 224 may be positioned at other locations along shaft 210.

The probe 200 includes a pair of conductors 226, 228 that are configured to place electrodes 222, 224, respectively, in electrical communication with controller 30 via cable 14 and/or connector 18. A distal end of conductor 226 is electrically coupled to electrode 222. A distal end of conductor 228 is electrically coupled to electrode 224. The connection between conductors 226, 228 to electrodes 222, 224, respectively, may be formed by any suitable manner of electrical or electromechanical connection, including without limitation soldering, brazing, welding, crimping, and/or threaded coupling. Cable 14 extends from a proximal end 213 of shaft 210, and may be supported by a strain relief 214.

Shaft 210 and electrodes 222, 224 may be formed by any suitable manner of manufacture. In an embodiment, shaft 210 may be formed by injection overmolding. By way of example only, shaft 210 may be formed from a high strength, electrically insulating material, e.g., fiber-reinforced polymer, fiberglass resin composite, long strand glass-filled nylon, and the like. During use, probe 200 may be inserted into tissue, placing electrodes 222, 244 into electrical communication with tissue thereby enabling sensor interface 34, and controller 30 generally, to obtain an impedance measurement thereof.

Turning to FIG. 5, a method 300 of operating an electromagnetic surgical ablation system having an ablation probe 100, and one or more tissue sensor probe(s) 200, is shown. The disclosed method begins in step 305 wherein one or more initializations may be performed, e.g., power-on self test (POST), memory allocation, input/output (I/O) initialization, and the like. In step 310, each of the tissue sensor probes to be used in the ablation procedure is designated as a threshold probe or a critical structure probe. In an embodiment, the user (e.g., a surgeon or an assisting practitioner) may manually input a corresponding designation for each tissue sensor probe. Additionally or alternatively, the tissue sensor probe may be automatically identified by an identifier included within the probe 200 and sensed by controller 30 and/or sensor interface 34 as described hereinabove.

A threshold value for each tissue sensor probe 200 may be established. In one embodiment, a threshold value for a threshold tissue sensor may differ from a threshold value for a critical structure tissue sensor. A threshold may be an absolute threshold, e.g., exceeding a fixed impedance value; a relative threshold, e.g., exceeding a predetermined change in impedance; or a rate threshold, e.g., where the rate of impedance change exceeds a predetermined rate. Other thresholds are contemplated within the scope of the present disclosure, including without limitation, spectral-based thresholds, wavelet-based thresholds, and impedance contour recognition thresholds.

The total number of tissue sensor probes designated for use during an ablation procedure may be represented as n. In step 315, the one or more tissue sensor probes are inserted into tissue in accordance with surgical requirements. In particular, a threshold probe is placed at or near an outer boundary of the desired ablation region, while a critical structure probe is positioned between the intended ablation region and a critical anatomical structure to be protected. In addition, an ablation probe 100 is positioned or inserted into tissue, e.g., the ablation site.

Once the ablation probe 100 and the one or more tissue sensor probes 200 have been positioned, the generator 20 is activated in step 320 to cause electromagnetic ablative energy to be delivered to tissue. Generally, activation of generator 20 will be effectuated in response to engagement of actuator 40. During the ablative energy delivery process, the impedance of each designated tissue sensor probe is monitored. In step 325 a monitoring loop is established wherein a tissue sensor probe counter x is initialized, e.g., set to address the first of the currently-utilized one or more tissue sensor probes 200, which may be expressed as probe(x). In step 330, an impedance value of the currently-addressed tissue sensor probe 200, which may be expressed as Zprobe(x), is compared to a corresponding threshold value. If Zprobe(x) does not exceed a corresponding threshold value, the method proceeds to step 335 wherein it is determined whether the generator is to be deactivated, e.g., the user has released actuator 40. If, in step 335, it is determined that the generator 20 is to be deactivated, in step 365 the generator is deactivated and the process concludes with step 370.

If, in step 335 it is determined that the generator 20 is to remain activated, in step 355 the tissue sensor probe counter x is incremented to address the next tissue sensor probe in use and in step 360, the tissue sensor probe counter is compared to the total number of tissue sensor probes designated for use. If in step 360 it is determined that the tissue sensor probe counter exceeds the total number of tissue sensor probes designated for use, the tissue sensor probe counter x is re-initialized in step 325; otherwise, the method continues with step 330 wherein the impedance value of a subsequent tissue sensor probe 200 is evaluated.

If, in step 330, it is determined that Zprobe(x) exceeds a corresponding threshold value, then in step 340 it is determined whether the currently-addressed tissue sensor probe, i.e., probe(x), is designated as a threshold probe or a critical structure probe. If probe(x) is a critical structure probe, then in step 350 an alarm indication is presented to the user, and step 365 is performed wherein the generator 20 is deactivated, which may help reduce possible damage to the critical structure corresponding to probe(x). If probe(x) is a threshold probe, then a status indication is presented to the user in step 345 (to indicate ablation progress status) and the method proceeds to step 335 as described hereinabove. In an embodiment, an additional test may be performed wherein it is determined whether all threshold probes currently in use, and/or all threshold probes within a designated probe group, have exceeded the corresponding threshold thereof, and, if so, continue with step 365 to deactivate generator 20.

It is to be understood that the steps of the method provided herein may be performed in combination and/or in a different order than presented herein without departing from the scope and spirit of the present disclosure.

The described embodiments of the present disclosure are intended to be illustrative rather than restrictive, and are not intended to represent every embodiment of the present disclosure. Further variations of the above-disclosed embodiments and other features and functions, or alternatives thereof, may be made or desirably combined into many other different systems or applications without departing from the spirit or scope of the disclosure as set forth in the following claims both literally and in equivalents recognized in law. The claims can encompass embodiments in hardware, software, firmware, microcode, or a combination thereof. 

What is claimed is:
 1. An ablation system, comprising: a generator adapted to selectively provide ablative energy; an ablation probe operably coupled to the generator and adapted to receive the ablative energy from the generator and to deliver the ablative energy to tissue; a controller operatively coupled to the generator, the controller including: a processor; a memory operatively coupled to the processor; a user interface operatively coupled to the processor; and a sensor interface circuit operatively coupled to the processor and adapted to receive at least one impedance sensor signal from at least one tissue sensor probe, the at least one tissue sensor probe operatively coupled to the controller, and including: a shaft having a proximal end and a distal end and adapted for insertion into tissue; a first electrode and a second electrode disposed on an outer surface of the shaft and adapted to operably couple to the sensor interface circuit to sense tissue impedance; and an identifier configured to transmit an electrical signal to the controller to identify the at least one tissue sensor probe as either a critical structure probe or a threshold probe.
 2. The ablation system in accordance with claim 1, wherein the controller includes an indicator that activates when a sensed tissue impedance parameter exceeds a predetermined threshold.
 3. The ablation system in accordance with claim 2, wherein the indicator is selected from the group consisting of a visual indicator, an audible indicator, and a haptic indicator.
 4. The ablation system in accordance with claim 1, wherein the controller is operable to deactivate the generator when a sensed tissue impedance parameter exceeds a predetermined threshold.
 5. The ablation system in accordance with claim 1, wherein the controller is configured to receive identification data from the identifier.
 6. The ablation system in accordance with claim 1, wherein at least one of the first and second electrodes is annular in shape and disposed coaxially about the shaft.
 7. The ablation system in accordance with claim 1, further including an actuator operatively coupled to the controller and configured to selectively activate the generator.
 8. The ablation system in accordance with claim 1, wherein the identifier includes at least one of an RFID tag, a semiconductor memory device and an encoded electrical component.
 9. An ablation system, comprising: a generator adapted to selectively provide energy; an ablation probe operably coupled to the generator and adapted to deliver energy to tissue; a plurality of tissue sensing probes, each of the plurality of tissue sensing probes including an identifier that identifies each of the plurality of tissue sensing probes as either a threshold probe or a critical structure probe; a controller configured to transmit an electrical signal to the identifier and determine whether each of the plurality of tissue sensing probes is a threshold probe or a critical structure probe and whether a sensed tissue impedance parameter from each of the plurality of tissue sensing probes exceeds a predetermined tissue impedance parameter threshold, wherein, for the critical structure probe, the predetermined tissue impedance parameter threshold is indicative of a pre-denaturation state of tissue and, for the threshold probe, the predetermined tissue impedance parameter threshold is indicative of denaturation of tissue.
 10. The ablation system in accordance with claim 9, wherein the controller is configured to automatically deactivate the generator in response to a determination that the sensed tissue impedance parameter from each of the plurality of tissue sensing probes exceeds the predetermined tissue impedance parameter threshold.
 11. The ablation system in accordance with claim 9, wherein the predetermined tissue impedance parameter threshold indicative of a pre-denaturation state of tissue is an initial rise in impedance.
 12. The ablation system in accordance with claim 9, wherein the predetermined tissue impedance parameter threshold indicative of denaturation of tissue is a rate of change of impedance exceeding a predetermined rate.
 13. The ablation system in accordance with claim 9, further comprising an actuator operatively coupled to the controller and configured to selectively activate the generator.
 14. The ablation system in accordance with claim 9, wherein the controller is configured to receive identification data from the identifier.
 15. The ablation system in accordance with claim 9, wherein the identifier includes at least one of an RFID tag, a semiconductor memory device and an encoded electrical component. 